- Annette Bening A. Indiana Jones Raiders of the Lost Ark (Harrison Ford)
- Eric Stoltz B. Penny Lane Almost Famous (Kate Hudson)
- Nicole Kidman C. Aragorn Lord of the Rings (Viggo Mortensen)
- Tom Cruise D. Dawn I Heart Huckabee's (Naomi Watts)
- Cate Blanchett E. Wolverine The X-Men (Hugh Jackman)
- Tom Selleck F. Mary Corleone The Godfather III (Sofia Coppola)
- Winona Ryder G. Jack Salmon The Lovely Bones (Mark Wahlberg)
- Brad Pitt H. Hanna Schmitz The Reader (Kate Winslet)
- Kate Winslet I. Marty McFly Back to the Future (Michael J. Fox)
- Ryan Gosling J. Anna Closer (Julia Roberts)
- Julianne Moore K. Deirdre Running With Scissors (Annette Bening)
- Stuart Townsend L. Nola Rice Match Point (Scarlett Johansson)
- Gwyneth Paltrow M. Tom/Tomas/Tommy The Fountain (Hugh Jackman)
- Dougray Scott N. Catwoman Batman Returns (Michelle Pfieffer)
- Sarah Polley O. Ren McCormack Footloose (Kevin Bacon)
1N- Annette Bening had been cast as Catwoman (beating out Sean Young who showed up in costume to audition and scared Tim Burton) but had to drop out when she became pregnant.
2I- Eric Stoltz was the original Marty McFly and even filmed for 5 week before director, Robert Zemeckis, decided it just wasn't working and that Stoltz wasn't funny enough.
3H- Kate Winslet had originally been approached to play Hanna, but had to decline because it conflicted with Revolutionary Road. Nicole Kidman was then cast. Weeks before it started to shoot, Kidman dropped out due to pregnancy. By this time, Revolutionary Road had finished filming and Kate was able to do the film that finally won her an Oscar.
4O- Due to the success of Risky Business, Cruise was set to star in Footloose, but had to drop out due to scheduling conflicts with All the Right Moves. Rob Lowe was then cast but injured his knee while preparing.
5J-Blanchett was attached to star in the film version of the play Closer, but dropped out after becoming pregnant. She also dropped out of the film version of The Merchant of Venice with Al Pacino at the same time.
6A- If Magnum, PI had had a different shooting schedule, the iconic fedora and whip would have been worn by Selleck.
7F- Ryder was set to play Al Pacino's daughter in the third Godfather movie, but dropped out before it started because of illness. She later revealed, during press for Girl, Interrupted, that she had checked in to a psychiatric hospital due to exhastion, anxiety, and depression.
8M- Remember when Pitt had a giant beard and long hair in the early 00's? Most wondered why the sexist man alive would go to such lengths to look homeless. But it was actually for Darren Aronofsky's The Fountain. He and Cate Blanchett were set to star, but the director lost the funding. By the time we was able to start it up again, Pitt had moved on.
9L- Most actors would love to star in a Woody Allen film, but Winslet backed out weeks before production rolled on Match Point because she decided to spend the summer with her family instead.
10G- A 20-something Ryan Gosling was cast as the father of a 13 year-old in Peter Jackson's film. Gosling showed up to set with a beard and 60 pounds of fat wanting to realistically look old enough to play her father. Jackson wasn't having it and fired him.
11K- As far back as 2002, Julianne Moore was set to star as the mother from hell in Running With Scissors. People were even predicting an Oscar win before it had even started rolling. But, she dropped out before production.
12C- Stuart Townsend was set to play Aragorn in all three of The Lord of the Rings movies and even trained for 2 months. A day before shooting, he was fired and replaced with Mortensen. Apparently, Townsend wasn't as commanding as they thought and they needed someone more mature. He wasn't even paid for his time.
13D- After the death of her father, Bruce Paltrow, Gwyneth dropped out of the production of Huckabee's a month before it started filming. She was also cast in the Maggie Gyllenhaal role in Happy Endings, but departed for the same reason.
14E- Poor Dougray Scott. The Scottish actor was cast as Wolverine in The X-Men series. But had to drop out when production on Mission Impossible II went over schedule. Instead the role made Hugh Jackman a star and most people don't even know who Scott is...
15B- For months Polley prepared for the role of Penny Lane, but quit before filming started because she didn't feel right about it. She was worried about the Hollywood production value and becoming too famous. She did a small Canadian film instead. Kate Hudson, who was orginaly cast as William's sister (Zooey Deschanel), took over the role and went on to receive an Oscar nomination and the fate that Polley avoided.